Ebola Disease

• Severe fatal disease in humans and nonhuman primates
• Named after a river in Democratic Republic of Congo
• One of the two members of the RNA viruses called the Filoviridae
• First three subgroups are known to cause disease in humans:
• Only subgroup to cause disease just in nonhuman primates:
• Exact origin, location, and natural habitat is unknown
• Originate in an animal host from Africa
• Mainly primates which carry it
• Ebola is usually spread within a health-care setting
• Cases of Ebola reported in: Democratic Republic of the Congo, Gabon, Sudan, the Ivory Coast, Uganda, and the Republic of the Congo.
• Infections with Ebola virus are severe
• No carrier state where the virus is located
• First patient becomes infected by contact with infected animal
• After thefirst person receives the virus, people can be exposed:
 from direct contact with the blood and/or secretions of an infected person.
 from contact with objects, such as needles, that have been contaminated with infected secretions
– sore throat – stomach pain
• After initial symptoms, hemorrhagic rash appears over entire body
• Patient bleeds from mouth and rectum
– immune systems failure to produce antibodies
• Diagnosing Ebola is very difficult
• Many symptoms can occur in other diseases

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