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Every year, 1,000 children with cystic fibrosis are born in the United States.

1 in 3,000 Caucasian babies have the disorder, making Cystic Fibrosis one

of the most common lethal genetic diseases in Caucasians. Overall, there are

30,000 Americans with Cystic Fibrosis, and an estimated 8 million people

carry one copy of the defective gene that causes the disease. These carriers

do not have symptoms of Cysitc Fibrosis, because a person must inherit t

two defective gene’s, one from each parent-to develop the disease. However,

each child of two Cystic Fibrosis carriers has a one in four chance of being

born with Cystic Fibrosis. You can now have testto identify couples at risk

for having children with Cystic Fibrosis.Improved therapy has transformed

Cystic Fibrosisfrom a disease, to a chronic illness, with most patients living

to adulthood. But despite this progress, there still is no cure for the disease

and most patients eventually will have infections of the airways and lung

failure. Since the 1989 identification of the gene which is altered in Cystic

Fibrosis, the pace of basic research has increased rapidly, and scientists

hope to translate new knowledge about the molecule basis of the disease to

new therapies to improve the lives of patients with this genetic disease. The

National Institute of Diabetes and Digestive and Kidney Diseases in

partnership with other components of the National Institutes of Health and

the Cystic Fibrosis Foundation, continues to foster research on the

molecular processes contributing to CF, exploration of gene therapy to cure

the disease, and efforts to develop other new and effective treatments.


The greatest symptom of Cystic Fibrosis is the excessive production of

thick, sticky mucus in the airways. Several factors may contr…

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